NeuroCoder

I've noticed some things running slower too, but I wasn't sure if my computer was getting older. As for the interface/asthetic, it's pretty terrible in every regard.

The figures in the nature article are worth it. Even my non-nerdy wife thought it was kind of interesting.

It's just very conversational. If you are comfortable with stats and just need a reference it can be obnoxious. I think I went through the first edition in my PhD and it was better than a stats course. But when I want a quick reference for something it is to much reading to get to the point. It might be more well organized now though.

As an MD/PhD I wish all MD researchers read this book. Heck, I wish all neuro researchers read it. If you are already established in in stats and math and your interest is just another math book to casually read or reference, this is a bad choice

Usually we test against best current treatment and not just always against placebo. If something clearly improves outcomes for a patient, it's unethical to not give them a treatment so that you can test your new intervention against a placebo.

Stress increases cortisol and cortisol for a long time wrecks the immune system. There are a lot of other things that effect cortisol levels, but it's at least on very plausible pathway for some getting sick more easily.

It's already an uphill battle to fix misinformation concerning vaccines without calling it political.

Article says this has been done other places already. Has this specifically been campaign ads or does it also involve things that are considered politically motivated messaging? For example, is there danger of vaccination PSAs getting banned because some politicians say bizarre things about them?

There are all kinds of presentations for seizures. Ones in the frontal lobe are particularly hard to catch based on external presentation. If one is suspected of having seizures they will get a continuously monitored EEG where times associated where the seizure like state is monitored electrically. Sometimes it's a really weird presentation of a seizure or sometimes it's psychogenic. Either way it's good to have these people get some help I'd it keeps happening.

Two things:

1. Blood brain barrier and CSF should be separate for all but tiny molecules. It's why CT angiograms are able to visualize distinct vessels. So it is pretty hard to directly interact with this sort of thing in vivo

2. A good chunk of the neuro community have been operating under the assumption that some of those mouse model findings are mechanisms in humans too. Since we couldn't easily prove it, people used a bunch of next best tools with fancy imaging that demonstrated it was very likely. On top of furter proof, this sort of study allows us to begin pinpointing exactly how close our next best tools are at estimating in vivo processes without opening up the head.

I wish I could, but in addition to this happening over a decade ago, he changed his lab's focus afterwards. He went into neurotransmitter research in skin since it has some overlapping embryological origins with the brain.

I had a neuroscience professor in undergrad who did a bunch of experiments where the only variables were things like the material of the cage, bedding, feeder, etc. He systematically tested variations in each separately. Outcomes varied in mice no matter what was changed. I would love to tell you what outcomes he measured, but it convinced me not to go into mice research so it's all just a distant memory.

On the other hand, I've worked with people since then who have their own mice studies going on. We are always learning new ways to improve the situation. It's just not a very impressive front page so it goes unnoticed by those not into mice research methods.

As in it has a higher inter rater reliability. The statistical term of reliability that is used when describing the likelihood to reproduce a measure under similar conditions.

Asperger's was not reliably diagnosable between healthcare workers trained to diagnose it. In other words, a diagnosis of Asperger's in someone's medical chart was not a reliable way of knowing if they had Asperger's.

It's the latter plus typing on my phone while riding the bus.