Kyrztyn

That is the problem with quick searches, they are usually incomplete.

1) While Biotinidase Deficiency is rare, Partial Biotinidase Deficiency is not as rare. Combining the two the incidence it is 1 in 61,000

2) There are no good statistics for late onset partial biotinidase deficiency. And they do not know why it happens. This is what I am diagnosed with.

3) Combine even a minimal decrease in biotinidase deficiency with a slight holocarboxylase synthetase deficiency and you can look like you have Biotinidase Deficiency when your enzyme assay is not that low. This can be cured with biotin as well. So how many is it now? 3000 or 300,000?

4) yes, there is more than BTD Deficiency that is wrong with me. I was stigmatized by doctors and psychiatrists for 25 years because all they saw was my mental illness. If it was not for Dr. Barry Wolf I would be dead.

5) so how many other causes of depression are there that do not get fixed with working out?

6) One of the people who authored this study is linked to Spring Health. Whose motto is “We use #data to help you choose the right #antidepressant”.

My point is that mood disorders are complex, and studies like this, that simplify mood disorders, are damaging to the people who have them. The company attached to this research is promising AI to find ways to help people’s mental health when there are currently no clear causes or treatments. I wonder if their app will tell people to get their B12 checked or send them to a doctor for Prozac when the jogging dies not work...

It’s vapor ware and they put out these studies to help them seem like they are not.

Aw, hearts!

:/

You established ZERO causality in your study! How can you even say you are a scientist and say this has a (potentially) large benefit?!

And you did not even distinguish between mental health and mental illness.

The fact that you are excited that you got a “positive response” from this article just tells me you are a neoliberal shill.

I’d be interested if your wife tests for Biotinidase Deficiency...? There are no “serious metabolic work ups” for mental health. Sure, they test thyroid, maybe iron and B12 if you press them. But beyond that?

I am telling you, as a person who suffered from suicidal depression, that seeing a pamphlet like that in the past would make me feel worse, not better. But why listen to me? I am only the patient.

#2, of course. Capitalism.

You want to bring the research to market, not help the mentally ill. You goal is profit.

For the 20 I have been “cared for” by people like you it took my own ingenuity and relentless pressure on a psychiatric system that thinks there is never a nutritional cause to mood disorders to have them test me for a biotinidase deficiency which turned up positive. My mood issues were cured by 15 grams of biotin a day.

Researched and doctors like you were so certain what caused my depression and anxiety you filled me with pills that rarely worked and diabled me with side effects. It took 15 years to even test me for a B12 or iron deficiency.

So sorry, but your study does not help the mentally ill. Maybe it helps people who are stressed from the everclenching fist of capitalism, but that’s about it.

They did not establish causality in the study, yet you would put it out for sick people already stigmatized and thinking they are “lazy”, “just need to get out of bed”, etc as another burden for them to carry?

Are you a sadist?

Let me give you a personal anecdote. I suffered depression and anxiety and fatigue for years. I tried to be active but it made me feel worse. Turns out I had late onset partial biotinidase deficiency. I take biotin, my depression and anxiety are gone and now I can work out like a normal person.

What good does this study do for people like me and the probably hundreds of thousands of people like me? I would in fact it harms people like me because it lays a simple cure over a complex and diverse issue.

Awesome.

Question:

Why are you wasting your time?

Do you wish to apply a blanket cure for the unknown multitude causes of mental health issues?

Why do you think reductions in the self reported “mental health” of the general population is useful for people who have been hospitalized with mood disorders?

Don’t you think that people who lie about how much exercise they do also might be lieing to themselves about their mental health?

This study was flawed from the start. They asked people if they were ever “diagnosed” with depression when there is no clear cause of depression. Depression can be lifelong, short term situational, caused by drugs, etc.

It also relied on self reported physical activity! Ha!

It is worthless to extract anything regarding mental heath and exercise from this study.

If these studies were not behind paywalls people might better understand what they mean.

They did not establish causality in the study and they also said that inactivity might be a symptom of poor mental health. The people who had less mental health days might not be physically ill, but rather, socially ill. If you read the full study and some of the interesting demographics you will see what I mean.

It really tells us nothing but puts more stigma on people who are ill making it seem like it is their fault they are sick.