Agree with "brand recognition" - its a serious advantage for employees of large corp.
Large corps are vulnerable to losing top talent because they usually can't match market due to strict internal hierarchy policies. Quicker way to get promoted at large corp - prove your skills, leave on good terms, gain visibility and titles elsewhere and then re-join large corp at a much higher position.
Regulations:
Large corps are much stricter regulated and this adds to your responsibilities to do boring stuff.
Permissions:
Large corps spending lots of resources for reinventing and improving systems of access controls and permissions as well as sets of exceptions to such systems.
Average worker age:
20+ something for startup, 40-50+ something for corps.
Accessibility of top management:
Startup: you knock the door and talk to the guy, Large corp: you send email to C*O of large corp and get no reply not because he is busy, but because his secretary pre-filtered emails and discarded yours.
Regulations:
Large corps are much stricter regulated and this adds to your responsibilities to do boring stuff.
Permissions:
Large corps spending lots of resources for reinventing and improving systems of access controls and permissions as well as sets of exceptions to such systems.
Average worker age:
20+ something for startup, 40-50+ something for corps.
Accessibility of top management:
Startup: you knock the door and talk to the guy, Large corp: you send email to C*O of large corp and get no reply not because he is busy, but because his secretary pre-filtered emails and discarded yours.