There was a question yesterday about Evidence Based Medicine vs Science Based Medicine. The SBM criticism of EBM is the over-reliance on Randomized Controlled Trials that meet p=0.05, without looking at the prior probability that a treatment would help.
For example, EMB would say that if you have an RCT that shows that a lucky rabbit's foot works, then you have reasonable evidence to put that into practice. The issue is that, as this article points out, even with a statistically significant result for such research, there's no plausible mechanism by which a rabbit's foot makes you lucky. Therefore the RCT is just one part of the whole picture, and subject to a specific type of manipulation.
For example, EMB would say that if you have an RCT that shows that a lucky rabbit's foot works, then you have reasonable evidence to put that into practice. The issue is that, as this article points out, even with a statistically significant result for such research, there's no plausible mechanism by which a rabbit's foot makes you lucky. Therefore the RCT is just one part of the whole picture, and subject to a specific type of manipulation.