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I noticed that PyPy does not show any real speed improvement over CPython in these benchmarks: https://www.techempower.com/benchmarks/

If you filter by Python, you can compare some results running on both CPython and PyPy. I would be curious to know what it is about these benchmarks that makes PyPy perform poorly. I would also be interested to see how Nuitka performs.

At the moment I'm also very excited about Pyston from Dropbox: https://github.com/dropbox/pyston