Yea, I know it's a really tired subject, but twitter really needs a major overhaul from a usability perspective. I think they should keep the 140 characters as a limit for what is shown in peoples feeds, but the character limit should be much higher. This is particularly important when you get into a conversation with many people, and the handles start taking up most of your 140 characters (as Marc Andreessen recently pointed out). It's also really hard to follow conversations, and they get separated somewhat arbitrarily. You might scoff and say that this would basically facebook-ize twitter, but honestly I don't think that's a bad thing. Facebook is moving into twitter's space, so twitter shouldn't be be so slow to act or it will get eaten, IMHO.
Also, I use twitter to keep up to date on some of the industries I'm interested in, and while it's a great tool it's still frustrating sometimes, since there is a flood of info throughout the day. TweetDeck makes it better since I can group things by interest and triage depending on how much time I have. I guess you can do that with the web interface but I have never found it as natural as with Tweetdeck.
Also, I use twitter to keep up to date on some of the industries I'm interested in, and while it's a great tool it's still frustrating sometimes, since there is a flood of info throughout the day. TweetDeck makes it better since I can group things by interest and triage depending on how much time I have. I guess you can do that with the web interface but I have never found it as natural as with Tweetdeck.