I've used Sennheiser HD595, Koss TBSE1 (which are basically the Audio Technica ATH-M50), Sennheiser eH-350 and the Philips Citiscape Downtown as my main headphones at some point and the Philips Uptown sound as good as the best of them.
My only gripe with them is the volume slider on the cord isn't great and is staticky when you touch it. As long as you keep it in its highest setting though then it's not a problem. I've used the headphones to take calls on my cell phone and no one has ever complained about audio quality.
I've used Sennheiser HD595, Koss TBSE1 (which are basically the Audio Technica ATH-M50), Sennheiser eH-350 and the Philips Citiscape Downtown as my main headphones at some point and the Philips Uptown sound as good as the best of them.
My only gripe with them is the volume slider on the cord isn't great and is staticky when you touch it. As long as you keep it in its highest setting though then it's not a problem. I've used the headphones to take calls on my cell phone and no one has ever complained about audio quality.