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Comment by dbbolton

>The farmers apparently take the drug themselves, at pretty high dosages, saying that it allows them to work without getting tiree.

That's insane. Tramadol is among the worst painkillers to use recreationally, which is why it's often the next line of analgesic therapy after NSAIDs and before hydrocodone.

It is a comparatively weak mu-opioid agonist, so the dose a person would have to take to get a prototypical opioid high, likely quadruple a normal prescribed dose at minimum, is pushing the margin of safety.

I am not advocating drug use here, but if you're dead set on getting high, please use something else- namely something with a higher mu-affinity that would require a lower dose, and ideally something that's not combined with acetaminophen or other NSAIDs.

parent dbbolton 12 years ago

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