Comment by zackzackzack

Or it could be that YC knows Mathematica and/or matlab are thinking about launching a cloud computing service. Mathematica definitely is and it will most likely ROFLstomp whatever these guys and other competitors are coming up with. Computer algebra systems and numerical analysis aren't just topics you can sprinkle with "Cloud" dust and have it come out right. Unless these guys have years of experience, YC probably made a prudent decision.