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Comment by i000

That is not true. For many diseases we lack good hypotheses about the underlying causal mechanisms which resulted in decades and billions being pumped into few questionable targets (e.g. amyloid and alzheimers). In other diseases such as many cancers we often lack "actionable" targets, resulting in hundreds me-too companies all chasing the same target with only subtle variations in approach (inefficient capital alocation).

So AI could help a lot in discovery, much more than the engineering like uses in antibody/drug optimization.

parent i000 10 days ago

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