I'm not sure. It's a philosophical issue: Nix defines itself as an implementation of a core theoretical idea. If you change that idea too much it may not be Nix anymore.
It's probably worth just going back to the drawing board and asking what the goals of a desktop OS should really be. You'd end up with something radically different to Nix, IMO, sort of like how how NeXT/macOS manages software is quite radically different to UNIX.
I actually have a little exploration of a new software distribution idea going on right now, but it's not trying to do the same things as Nix. It starts by asking what a desktop OS inspired by the success of the web would look like.
It's probably worth just going back to the drawing board and asking what the goals of a desktop OS should really be. You'd end up with something radically different to Nix, IMO, sort of like how how NeXT/macOS manages software is quite radically different to UNIX.
I actually have a little exploration of a new software distribution idea going on right now, but it's not trying to do the same things as Nix. It starts by asking what a desktop OS inspired by the success of the web would look like.