Just out of curiosity: is it possible to somehow attach an ISA Adapter via USB to a VM? ISA does depend a lot on DMA and timing, but the clock is only 8 mhz and gives a software layer on a modern cpu a lot of time to do stuff between ISA bus cycles.
Keeping old hardware running is very fragile. Most spare parts are decades old now too, and nobody knows if they still work properly.
Keeping old hardware running is very fragile. Most spare parts are decades old now too, and nobody knows if they still work properly.