How do geneticists go about identifying alleles associated with autism? Seems like the effect size would be very small for most of them, and given the relatively small sample population of humans that can be practically sequenced for this, it seems difficult to separate true signal from statistical noise.
Also is it actually just “a sum of cumulative effects of these alleles crossing a threshold causes autism” or more complex like “Allele A and B together has a very significant effect, A and C has a moderate effect but A, B, and C together is has no effect”
Also is it actually just “a sum of cumulative effects of these alleles crossing a threshold causes autism” or more complex like “Allele A and B together has a very significant effect, A and C has a moderate effect but A, B, and C together is has no effect”