Comment

Comment by Utkarsh_Mood

While AlphaFold is great, to my knowledge, these proteins have several non-significant IDRs (intrinsically disordered regions), which have been and continue to be hard to model with AlphaFold. I work on computational modeling, so if I had to guess, I'm very unsure if people are using it for whole protein modeling, rather than looking at more specific domains where it probably does much better.
parent Utkarsh_Mood 2 months ago

No comments yet

Be the first to share your thoughts.

Live from the official Hacker News API

A modern reader for Hacker News · SvelteKit + Skeleton