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Comment by vector_spaces

There has been some research on spearmint suggesting anti-androgen effects in PCOS, which is a bit unexpected to me as I wouldn't expect mint-family herbs to have much hormone modulating effect at all. I would imagine there to be similarities in profile between spearmint and peppermint so perhaps a related mechanism is involved, although I would probably expect the opposite outcome as a naive layperson. But I haven't closely evaluated the paper nor do I know whether there's been much else suggesting this

It is important to remember that herbs are difficult to study in this setting compared with isolated compounds -- likely because their pharmacological and chemical compositions are sensitive to many factors: hour and season of harvest, form consumed (raw powder, alcohol extract, cold water infusion, fat emulsion, hot water infusion, combustion, pyrolysis, essential oil), part consumed (leaf, root, flower, seed), among staggeringly many others. Anyone with experience consuming cannabis or coffee can probably testify to the above

Not to mention that the pharmacologically active compounds in many plants are far from being comprehensively understood, let alone their interactions and dynamics

This isn't to say that every claim about herbs is to be taken seriously. My point here is more that there is no good reason to dismiss the herb itself as a cause yet simply because it's an herb and a fairly mundane one at that. There are easy examples of herbs which have pronounced physiological effects, used for recreation, performance enhancement, as literal poison, to induce labor, to thin the blood -- among others.

https://pubmed.ncbi.nlm.nih.gov/19585478/

parent vector_spaces 2 months ago

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