Interesting. Part of the reason I was eager to use retatrutide was the reversibility. Fantastic drug and entirely reversible. I self-tested and the effects I had on it were reversed entirely in its absence. Similar to caffeine or amphetamine at the doses I have tried (which are not high), removing the intervention resulted in a return to a prior state over a fairly short period. I'd say that, in general, some of the good properties essential to an intervention for a non-debilitating condition are:
* uniform dose-response: easy to increase effect by changing dose
* reversibility: automatic reversion to pre-intervention in a short-term is gold standard - allows for regret escape
* low-cost
GLP-1 drugs have these properties which I like. I'm surprised to hear that someone would prefer the alternative, but I must imagine that cost and the dosing structure (sub-q injection is annoying) must dominate decision making here.
* uniform dose-response: easy to increase effect by changing dose
* reversibility: automatic reversion to pre-intervention in a short-term is gold standard - allows for regret escape
* low-cost
GLP-1 drugs have these properties which I like. I'm surprised to hear that someone would prefer the alternative, but I must imagine that cost and the dosing structure (sub-q injection is annoying) must dominate decision making here.