They had bet 100% on it killing PA-RISC and DEC Alpha. They ported HP-UX, OpenVMS and NonStop to it. All 3 of them were tangled up in long running enterprise and government contracts.
They since discontinued HP-UX, offloaded OpenVMS and ported NonStop to x86-64.
They since discontinued HP-UX, offloaded OpenVMS and ported NonStop to x86-64.