Given that fertility rates are currently plummeting worldwide, the principles of natural selection would dictate that humans are currently undergoing very high selection pressure for specific traits.
Basically, any genetic trait that causes people today to think "You know, I think I'm going to remain childfree" is specifically selected against, and any trait that causes people to want more children will be selected for. I'd argue that the invention of reliable birth control was that biggest change in human selective pressures in history. Evolution made sex highly pleasurable and desirable because it often resulted in passing on your genes. That's no longer true with reliable birth control, and with such a huge environmental shift natural selection will act on other avenues that cause people to have children.
Basically, any genetic trait that causes people today to think "You know, I think I'm going to remain childfree" is specifically selected against, and any trait that causes people to want more children will be selected for. I'd argue that the invention of reliable birth control was that biggest change in human selective pressures in history. Evolution made sex highly pleasurable and desirable because it often resulted in passing on your genes. That's no longer true with reliable birth control, and with such a huge environmental shift natural selection will act on other avenues that cause people to have children.