The Pubmed articles are from 20 years ago. The 2023 JAMA article has some qualified information:
"In 2021, US poison centers received more than 80 000 cases involving an acetaminophen product.1 The National Electronic Injury Surveillance System estimated that 78 414 emergency department (ED) visits occurred annually in the US from January 1, 2006, through December 31, 2007, for overdoses of acetaminophen-containing products.2 In Canada, approximately 4500 hospitalizations occur each year because of acetaminophen overdose.3"
It doesn't tell us risk. Acetaminophen is very widely used, potentially the most widely used drug. I'm not sure what these numbers represent in terms of risk.
"In 2021, US poison centers received more than 80 000 cases involving an acetaminophen product.1 The National Electronic Injury Surveillance System estimated that 78 414 emergency department (ED) visits occurred annually in the US from January 1, 2006, through December 31, 2007, for overdoses of acetaminophen-containing products.2 In Canada, approximately 4500 hospitalizations occur each year because of acetaminophen overdose.3"
It doesn't tell us risk. Acetaminophen is very widely used, potentially the most widely used drug. I'm not sure what these numbers represent in terms of risk.