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Comment by reenorap

This finding of shingles and dementia is likely due to “healthy vaccinee” bias as per the link someone else posted below:

https://youtu.be/qlTnnQytOJ0?is=XJ0c5pWVV6Lg0IMs

As per one of the slides around 7 minutes in, there are many vaccines that show a 20-40% reduction in mortality and dementia.

The talk above basically says that “observational studies” may show great results, like the so-called protective action of the shingles vaccine against dementia. However when brought to a well designed RCT all those benefits don’t actually show up. And the speaker shows later on that the shingles vaccines shows a marked benefit for shingles but nothing for dementia.

parent reenorap 3 months ago

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