When it comes to large assets, wasting large chunks of space is a problem. If your chunks are 64 kib average (from the Lore document), but changes only average 1 kib (which could be a high estimate), then you will still run out of space 64 times faster and need to read 64 times more data off of the disk for certain operations.
It also makes diffing hard, as well as diff viewing.
It also makes diffing hard, as well as diff viewing.