Well, of course the idea of DJNZ was to implement a very common pattern (decrement a register and jump (normally backwards) if the result was not zero) - this tended to simplify code rather than make it more complex.
> However I couldn't keep all instructions and timings in my head.
I was never really interested in the timings, but I did get to the stage (not by conscious memorisation) of being able to assemble and disassemble Z80 code in my head, with some accuracy.
> I preferred, however, the fact that I/O was memory mapped on the 6502.
Many (most?) Z80 systems used memory mapped I/O. It's down to the hardware designer.
> the complexity of some instructions (e.g. DJNZ)
Well, of course the idea of DJNZ was to implement a very common pattern (decrement a register and jump (normally backwards) if the result was not zero) - this tended to simplify code rather than make it more complex.
> However I couldn't keep all instructions and timings in my head.
I was never really interested in the timings, but I did get to the stage (not by conscious memorisation) of being able to assemble and disassemble Z80 code in my head, with some accuracy.
> I preferred, however, the fact that I/O was memory mapped on the 6502.
Many (most?) Z80 systems used memory mapped I/O. It's down to the hardware designer.