Yea, this is currently the confusing part of running local models for newbies: Even after you have decided which model you want to run, and which org's quantizations to use (let's just assume Unsloth's for example), there are often dozens of quantizations offered, and choosing among them is confusing.
Say you have a GPU with 20GB of VRAM. You're probably going to be able to run all the 3-bit quantizations with no problem, but which one do you choose? Unsloth offers[1] four of them: UD-IQ3_XXS, Q3_K_S, Q3_K_M, UD-Q3_K_XL. Will they differ significantly? What are each of them good at? The 4-bit quantizations will be a "tight squeeze" on your 20GB GPU. Again, Unsloth steps up to the plate with seven(!!) choices: IQ4_XS, Q4_K_S, IQ4_NL, Q4_0, Q4_1, Q4_K_M, UD-Q4_K_XL. Holy shit where do I even begin? You can try each of them to see what fits on your GPU, but that's a lot of downloading, and then...
Once you [guess and] commit to one of the quantizations and do a gigantic download, you're not done fiddling. You need to decide at the very least how big a context window you need, and this is going to be trial and error. Choose a value, try to load the model, if it fails, you chose too large. Rinse and repeat.
Then finally, you're still not done. Don't forget the parameters: temperature, top_p, top_k, and so on. It's bewildering!
1: https://huggingface.co/unsloth/Qwen3.6-27B-GGUF
Say you have a GPU with 20GB of VRAM. You're probably going to be able to run all the 3-bit quantizations with no problem, but which one do you choose? Unsloth offers[1] four of them: UD-IQ3_XXS, Q3_K_S, Q3_K_M, UD-Q3_K_XL. Will they differ significantly? What are each of them good at? The 4-bit quantizations will be a "tight squeeze" on your 20GB GPU. Again, Unsloth steps up to the plate with seven(!!) choices: IQ4_XS, Q4_K_S, IQ4_NL, Q4_0, Q4_1, Q4_K_M, UD-Q4_K_XL. Holy shit where do I even begin? You can try each of them to see what fits on your GPU, but that's a lot of downloading, and then...
Once you [guess and] commit to one of the quantizations and do a gigantic download, you're not done fiddling. You need to decide at the very least how big a context window you need, and this is going to be trial and error. Choose a value, try to load the model, if it fails, you chose too large. Rinse and repeat.
Then finally, you're still not done. Don't forget the parameters: temperature, top_p, top_k, and so on. It's bewildering!
1: https://huggingface.co/unsloth/Qwen3.6-27B-GGUF