I can speak anecdotally, at least.
My shoulders are pretty wide for my frame. When using most laptop keyboards and many standard keyboards, I have to tuck my shoulders in and twist my wrists. This was causing some serious pain and tension in my neck, shoulders, and wrists, likely leading toward carpal tunnel.
I made two different changes in succession that helped greatly (and I don't remember the order now):
1. With a split keyboard, the halves could be placed so my wrists are straight and my arms hold at shoulder-width, and this rapidly reduced the amount of tension I was experiencing and gradually eased my wrist issues. Tenting the keyboard and getting a vertical mouse helped as well, but I'd rate those as minor improvements, especially since I aim not to drive with the mouse as much.
2. With Colemak layout, I was able to gradually transition from QWERTY (there's a series of AHK scripts I found at the time that basically rotated triples of keys). This helped reduce wrist strain at the hand level.
My shoulders are pretty wide for my frame. When using most laptop keyboards and many standard keyboards, I have to tuck my shoulders in and twist my wrists. This was causing some serious pain and tension in my neck, shoulders, and wrists, likely leading toward carpal tunnel.
I made two different changes in succession that helped greatly (and I don't remember the order now):
1. With a split keyboard, the halves could be placed so my wrists are straight and my arms hold at shoulder-width, and this rapidly reduced the amount of tension I was experiencing and gradually eased my wrist issues. Tenting the keyboard and getting a vertical mouse helped as well, but I'd rate those as minor improvements, especially since I aim not to drive with the mouse as much.
2. With Colemak layout, I was able to gradually transition from QWERTY (there's a series of AHK scripts I found at the time that basically rotated triples of keys). This helped reduce wrist strain at the hand level.