Comment by yashasolutions

I have seen people rewrite entire application from React to htmx. It works. But the architecture required is a tad different. Also you need Alpine as a complementary library for the reactive parts. (I mean you could do a lot just with htmx but I find Alpine more convenient in many places when I need to work with json - since I don't control all backend and json isn't really a first class citizen of htmx)