I doubt it. C is well within 2x of what you can achieve with hand written assembly in almost every case.
Furthermore writing large programs in pure assembly is not really feasible, but writing large programs in C++, Go, Rust, Java, C#, Typescript, etc. is totally feasible.
Furthermore writing large programs in pure assembly is not really feasible, but writing large programs in C++, Go, Rust, Java, C#, Typescript, etc. is totally feasible.