I will again mention my favorite cancer champions, the bats.
Bats very rarely get cancer (I tried to find the actual # of verified cases of cancers in bats, but came up short), and they have a lot of anti-cancer adaptations in their genome.
They are also really good at taming inflammation and activity of various viruses. That helps them survive infection with rabies - their systems just don't react as aggresively to the infection as ours (and most mammals') do.
This may help them against cancer as well. Not just p53 et al.
Bats very rarely get cancer (I tried to find the actual # of verified cases of cancers in bats, but came up short), and they have a lot of anti-cancer adaptations in their genome.
They are also really good at taming inflammation and activity of various viruses. That helps them survive infection with rabies - their systems just don't react as aggresively to the infection as ours (and most mammals') do.
This may help them against cancer as well. Not just p53 et al.