Not leaving the keyboard is one big thing. I ditched webkit for Firefox in order to be able to use Pentadactyl, but it's worth it to not have to leave the home row.
Learning a few commands is not hard, and there is always the ol' mouse to fall back upon if you don't want to remember all those commands.
Learning a few commands is not hard, and there is always the ol' mouse to fall back upon if you don't want to remember all those commands.