Comment by gibybo

Yes, and you would almost certainly want to automate it with a filter wheel that changes the filters for you on a schedule. However, a key advantage of a mono camera is that you don't have to limit yourself to RGB filters. You can use some other set of filters better suited for the object you are capturing and map them back to RGB in software. This is most commonly done with narrowband filters for Hydrogen, Sulfur and Oxygen which allow you to see more detail in many deep space objects and cut out most of the light pollution that would otherwise get in your way.