Comment by codytruscott

Rather than 23andMe, Ancestry ($50-$100) etc => imputation, broad clinical labs offers exome + genome blended for $120.

https://usegalaxy.org is pretty remarkable and provides access to a ton of open source bioinformatics tools + compute to process the files.

I really think the $1200 20x pacbio from broad is worth it if you are going to make it serious hobby.