Comment by OJFord

I think a better title here than:

> The first non-opoid [sic] painkiller

might be:

> The first non-opioid nociceptive pain-killer

Nociceptive pain being that by actual damage to tissue, as opposed to neuropathic pain like a headache or inflammation that you might take a (non-opioid!) NSAID for.

https://www.iasp-pain.org/resources/terminology/