Large prospective cohort study (103 388 participants) showing that artificial sweeteners and specifically aspartame are associated with increased risk of cardiovascular disease: https://www.bmj.com/content/378/bmj-2022-071204
"...findings indicate that these food additives, consumed daily by millions of people and present in thousands of foods and beverages, should not be considered a healthy and safe alternative to sugar..."
Also, artificial sweeteners might not help with obesity: "Long-term aspartame and saccharin intakes are related to greater volumes of visceral, intermuscular, and subcutaneous adipose tissue: the CARDIA study" https://www.nature.com/articles/s41366-023-01336-y
"...findings indicate that these food additives, consumed daily by millions of people and present in thousands of foods and beverages, should not be considered a healthy and safe alternative to sugar..."
Also, artificial sweeteners might not help with obesity: "Long-term aspartame and saccharin intakes are related to greater volumes of visceral, intermuscular, and subcutaneous adipose tissue: the CARDIA study" https://www.nature.com/articles/s41366-023-01336-y