It's basically impossible. The sites that manage to be strict enough just end up with bots which are real phones in a building somewhere.
You just have to design so the bot's aren't relevant. The problem with Twitter, Facebook, and friends, is that they push the bot content at you, even if you don't follow them.
You just have to design so the bot's aren't relevant. The problem with Twitter, Facebook, and friends, is that they push the bot content at you, even if you don't follow them.