Comment by HDMI_Cable

I completely agree—though it would be very difficult to measure the information contained within methylation/acetylation. If, naively, we assume that epigenetic modifications act only to increase or decrease the rate of transcription (or promoter binding, nucleosome coverage, and/or things we barely even understand as of now), and also assume that only cytosine bases are modified, then we still increase our estimate for the amount of information by at least an order of magnitude—and this neglects other modifications like methylation on nucleosomes, of which there are hundreds.