Comment by vince14

Because projects like these were missing back then, I got creative with nginx and do not need any config changes to serve new projects:

  server {
    listen 80;
    server_name ~^(?<sub>\w+)(\.|-)(?<port>\d+).*; # projectx-20201-127-0-0-1.nip.io
    root sites/$sub/public_html;
    try_files $uri @backend;
    location @backend {
      proxy_pass http://127.0.0.1:$port;
      access_log logs/$sub.access;
    }
  }

Configuration is done via the domain name like projectx-20205-127-0-0-1.nip.io which specifies the directory and port.

All you need to do is create a junction (mklink /J domain folder_path). This maps the domain to a folder.