Comment by karparov

It's the exact opposite of math.

Math postulates a bunch of axioms and then studies what follows from them.

Natural science observes the world and tries to retroactively discover what laws could describe what we're seeing.

In math, the laws come first, the behavior follows from the laws. The laws are the ground truth.

In science, nature is the ground truth. The laws have to follow nature and are adjusted upon a mismatch.

(If there is a mismatch in math then you've made a mistake.)