Comment Comment by arcticbull SSRIs aren’t shown to be much better than placebo and are shown to be about as effective as therapy — which is actually durable.There’s also rates of sexual side effects in excess of 70% [1] and they cause weight gain which is separately associated with depression.In fact industry data shows a smaller gap between SSRIs and placebo than FDA data. See Figure 1. [2]The problem with SSRIs is that serotonin receptors are all over the body including in the gonads and they play a large role in appetite regulation.They do something but it’s not nearly what people assume.[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6007725/[2] https://pmc.ncbi.nlm.nih.gov/articles/PMC4592645/ parent arcticbull 1 year ago
There’s also rates of sexual side effects in excess of 70% [1] and they cause weight gain which is separately associated with depression.
In fact industry data shows a smaller gap between SSRIs and placebo than FDA data. See Figure 1. [2]
The problem with SSRIs is that serotonin receptors are all over the body including in the gonads and they play a large role in appetite regulation.
They do something but it’s not nearly what people assume.
[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6007725/
[2] https://pmc.ncbi.nlm.nih.gov/articles/PMC4592645/