>"In the episode, the character Liz Lemon, portrayed by Tina Fey, complains to character Jack Donaghy, portrayed by Alec Baldwin, about having finished a hard week of work, with Donaghey reminding her that it is still Wednesday"
but "what a week" by itself does not indicate that the week is over, you can say "what a week" in the middle of a week; it would imply more the multiplicity of things that have already gone wrong, and "it's Wednesday" as a response has the sense "and it's only Wednesday, more things can still happen"
>"In the episode, the character Liz Lemon, portrayed by Tina Fey, complains to character Jack Donaghy, portrayed by Alec Baldwin, about having finished a hard week of work, with Donaghey reminding her that it is still Wednesday"
I don't know any context beyond what's in this clip of Liz Lemon saying it to Jack https://www.youtube.com/watch?v=1z3uGyBM_1c
but "what a week" by itself does not indicate that the week is over, you can say "what a week" in the middle of a week; it would imply more the multiplicity of things that have already gone wrong, and "it's Wednesday" as a response has the sense "and it's only Wednesday, more things can still happen"