Alzheimer's may not be primarily a brain disease but rather an autoimmune disorder where the brain's immune system mistakenly attacks its own cells, with beta-amyloid playing a central role.
There is a growing consensus that focusing solely on beta-amyloid has led to stagnation in treatment development, prompting researchers to explore alternative theories and treatment pathways.
Also there is potential fabrication of data in a key 2006 study linking beta-amyloid to Alzheimer's and the FDA's approval of aducanumab, which has faced criticism for its incomplete data.
https://www.sciencealert.com/alzheimers-may-not-actually-be-...
Alzheimer's may not be primarily a brain disease but rather an autoimmune disorder where the brain's immune system mistakenly attacks its own cells, with beta-amyloid playing a central role.
There is a growing consensus that focusing solely on beta-amyloid has led to stagnation in treatment development, prompting researchers to explore alternative theories and treatment pathways.
Also there is potential fabrication of data in a key 2006 study linking beta-amyloid to Alzheimer's and the FDA's approval of aducanumab, which has faced criticism for its incomplete data.