Comment by echelon

Instead of amyloid and tau, we now have a bunch of promising new leads:

- insulin and liver dysregulation impacting the brain downstream via metabolic dysfunction

- herpesviruses crossing the blood brain barrier, eg after light head injury or traveling the nervous system

- gut microbiota imbalance causing immune, metabolic, or other dysregulation

- etc.

These same ideas are also plausible for MS, ADHD, etc.