Comment by crest

Most CPUs suitable to implement such a protocol can do endian swapping for free e.g. a load+bswap instruction, a microarchitecture that fuses load+bswap. Don't worry about byte swapping fixed sized int across the network. Just keep in mind that for some applications it maters e.g. most bignum operations favour little endian, but databases profit from big endian (memcmp sorts in numerical order).