Comment by trhway

It is the napkin scale, not precise mission calculation. Doing 2 stages you can get faster, doing higher voltage you can get faster, etc. Slow down would of course take time and delta-v, changing observation station would also take them, etc. What interesting is that increasing Isp 10x seems to be doable with the today's/near-future tech, and that would even allow 1000 year mission to the closest star using 3 stages (unfortunately even my napkin breaks though when trying to stretch to the 100 years mission to the star using the today's/near-future tech).