Comment by diath

Last year I was hospitalized and quarantined for Tuberculosis, which is fairly strong against antibiotics so the antibiotic therapy is 6 months long (minimum), and that's precisely how I was treated, by combining first 4 then 2 antibiotics in order to prevent the bacteria from developing resistance, but you're right, it's super bad for your liver, I've seen heavy alcoholic patients in the same ward that were refused treatment because "we would destroy your barely functioning liver and kill you", and watched them just die, but I don't think it completely prevents the bacteria from building resistance, it just minimizes the odds to a significant degree.