Comment by lepus

Psychedelics aren't to be taken lightly and should never be first line treatment in my opinion. They can pull down your defense mechanisms, some of which can be very strong, and if you're not ready for it then it can definitely leave you worse off. That doesn't mean they don't have value in a carefully controlled set/setting and dose. Accepted treatments like ECT can absolutely also leave you worse off but in the right people the risk is worth the potential payoff for both.