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Comment by SatvikBeri
Our 30kloc Julia codebase only has one key macro, but it's a really important one. It's ~70 lines of code that's saved us ~5,000 loc, and more importantly let researchers do a lot of stuff that would need normally need more programming expertise. We might be able to live without it, but it would have cost us a significant amount of time maintaining and debugging, and a much slower research feedback loop.