Comment by nybsjytm

>The alphafold work has been used across the industry (successfully, in the sense of blind prediction), and has been replicated independently.

This is clearly an overstatement, or at least very incomplete. See for instance https://www.nature.com/articles/s41592-023-02087-4:

"In many cases, AlphaFold predictions matched experimental maps remarkably closely. In other cases, even very high-confidence predictions differed from experimental maps on a global scale through distortion and domain orientation, and on a local scale in backbone and side-chain conformation. We suggest considering AlphaFold predictions as exceptionally useful hypotheses."