I once read an off hand comment[1] from a dental scientist on Reddit that NovaMin® (calcium sodium phosphosilicate) was shown with strong evidence to reverse tooth decay and promote remineralization but due to complex licensing issues was made OTC in Sensodyne toothpaste everywhere but the USA.
I think the effect is subtle but present and slightly more effective than just fluoride by itself. I travel often enough that I find myself looking for and buying Sensodyne with novamin but without whitening agents when I’m abroad but I understand others source it in the US online. Do check the ingredients - it’s in about 1/3rd of the Sensodyne packages I pick up off the shelf outside the US but certainly not all.
I follow the topic very casually - I understand hydroxyapatite, fluorapatite, and biotin were initially reported to be even better (but only through self-reported studies such as Biomin.) I couldn’t tell you why or if there is now more credibility there nor where to source it if it is. BioMin USA’s anti-fluoride stance raises a lot of red flags for me and is probably what turned me off their brand when I looked into it years ago. GSK Sensodyne sells formulations with fluoride and novamin - I wouldn’t use toothpaste without fluoride. (Edit: I see BioMin UK sells toothpaste with fluoride.)
I think the effect is subtle but present and slightly more effective than just fluoride by itself. I travel often enough that I find myself looking for and buying Sensodyne with novamin but without whitening agents when I’m abroad but I understand others source it in the US online. Do check the ingredients - it’s in about 1/3rd of the Sensodyne packages I pick up off the shelf outside the US but certainly not all.
I follow the topic very casually - I understand hydroxyapatite, fluorapatite, and biotin were initially reported to be even better (but only through self-reported studies such as Biomin.) I couldn’t tell you why or if there is now more credibility there nor where to source it if it is. BioMin USA’s anti-fluoride stance raises a lot of red flags for me and is probably what turned me off their brand when I looked into it years ago. GSK Sensodyne sells formulations with fluoride and novamin - I wouldn’t use toothpaste without fluoride. (Edit: I see BioMin UK sells toothpaste with fluoride.)
[1] https://elemental.medium.com/why-is-the-internet-obsessed-wi... - Medium Paywall link but gets the general point across