Comment Comment by Footkerchief Missing mention of pawpaw's annonacin content, which causes Parkinsonism.https://pubmed.ncbi.nlm.nih.gov/22130466/"Pawpaw fruit contains a high concentration of annonacin, which is toxic to cortical neurons."https://www.mskcc.org/cancer-care/integrative-medicine/herbs..."Pawpaw fruit contains high concentrations of annonacin, which is toxic to nerve cells. In addition there have been case reports of possibly related nerve toxicity. Therefore, chronic use should be avoided." parent Footkerchief 2 years ago
https://pubmed.ncbi.nlm.nih.gov/22130466/
"Pawpaw fruit contains a high concentration of annonacin, which is toxic to cortical neurons."
https://www.mskcc.org/cancer-care/integrative-medicine/herbs...
"Pawpaw fruit contains high concentrations of annonacin, which is toxic to nerve cells. In addition there have been case reports of possibly related nerve toxicity. Therefore, chronic use should be avoided."