I recently migrated over to NixOS which treats systemd as the source of truth for everything, including containers. I found this model extremely intuitive, but it was difficult to apply this to Docker Compose without a lot of manual migration. So I ended up writing a tool that handles this for you — it converts your Compose files into a NixOS config that can be interpreted and managed natively.
https://github.com/aksiksi/compose2nix