Mixtral works great at 3-bit quantization. It fits onto a single RTX 3090 and runs at about 50 tokens/s. The output quality is not "ruined" at all.
For the amount of money you're talking about, you could also buy two 3090s (~$750 each on eBay) and have 48GB of VRAM to run with less quantization at full speed.
M-series Macs are surprisingly flexible platforms, but they're not "the only" consumer platform that can do Mixtral.
For the amount of money you're talking about, you could also buy two 3090s (~$750 each on eBay) and have 48GB of VRAM to run with less quantization at full speed.
M-series Macs are surprisingly flexible platforms, but they're not "the only" consumer platform that can do Mixtral.